Nature

A combinatorial approach to hybrid enzymes independent of DNA homology

We present a methodology, termed incremental truncation for the creation of hybrid enzymes (ITCHY), that creates combinatorial fusion libraries between genes in a manner that is independent of DNA ...
Nature

Reference genome sequence and population genomic analysis of peas provide insights into the genetic basis of Mendelian and other agronomic traits

Sequence alignment and genetic variation calling To detect SNPs in populations, raw reads of DNA were filtered to remove sequencing adapters and low-quality bases using fastp (v.0.12.2) with the ...
AHA/ASA Journals

Contrastive Machine Learning to Quantify Hypertensive Multiorgan Damage and Identify New Disease Phenotypes: A Multinational Multimodal Study

BACKGROUND: Hypertension induces structural and functional damage in multiple organs. Evidence of subclinical damage ...
Entrepreneur

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