Researchers have developed a chronic intranasal rotenone mouse model that reproduces the brain-first, olfactory-to-midbrain ...
Parkinson's disease is the second most common neurodegenerative disease. Over the last 30 years, studies have shown that a ...
Scores on a clinical evaluation tool for motor symptoms of Parkinson’s disease stabilized with rexaceract, according to data ...
A new preclinical study shows that trigonelline, a coffee-derived alkaloid, reduces alpha-synuclein pathology and ...
BOSTON, Oct. 7, 2025 /PRNewswire/ -- WaveBreak announced today the presentation of human brain tissue data demonstrating that WTX-607, a first-in-class small molecule clinical candidate for the ...
In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils. Parkinson's ...
Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's ...
The protein alpha-synuclein is abundant in healthy brains and plays an important role in enabling communication between nerve ...
Alector (NASDAQ:ALEC) outlined its strategy to advance brain-penetrant therapies for neurodegenerative diseases, highlighting an anti-amyloid beta antibody for Alzheimer’s disease and two siRNA ...
Scientists have, for the first time, directly visualized and quantified the protein clusters believed to trigger Parkinson's, marking a major advance in the study of the world's fastest-growing ...