"Synaptic vesicles are of paramount importance in brain function and they have been studied for decades. However, previous reports have described the molecular composition of an 'average' synaptic ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with ...

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

For all its mysteries, the brain can sometimes be described through simple metaphors. For example, communication between neurons works in many ways like a busy shipping depot: components come in, ...

For decades, neuroscientists have debated whether synaptic vesicles “kiss-and-run” or do an irreversible “full collapse” when releasing neurotransmitters. Now, a team in China has frozen that moment ...

In A, researchers used a fluorescent protein (synaptopHluorin) to visualize synaptic vesicle movement. Some vesicles stay open briefly before retrieval (kiss-and-run). Others stay open longer but also ...

Researchers at the Hong Kong University of Science and Technology (HKUST) have thrown new light on the mechanism for how vesicles move short distances within specific parts of the cell, an area not ...

Video depiction of vesicle fusion and tethering. In the active zone in the central left of the video, docked vesicles (dark blue) fuse with the membrane, releasing their contents and being quickly ...

Max Delbrück Center for Molecular Medicine in the Helmholtz Association Researchers led by Uljana Kravčenko and her colleagues in the lab of Professor Misha Kudryashev, Group Leader of the In Situ ...