Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...

Researchers from Kyushu University discovered a previously unrecognized synaptic "hotspot" that forms during adolescence, challenging the long-held view that adolescent brain development was dominated ...

Neuroplasticity and development have traditionally focused on synaptic mechanisms as the primary substrates of circuit remodeling. However, recent advances ...

The first analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...

Researchers developed SynTrogo, a molecular tool enabling targeted synapse removal via engineered neuron–astrocyte ...

The Kobe University-led research team identified a group of proteins that undergo a phase of change where some are produced more and others are produced less as time passes. They also found that the ...