Cell segmentation is the foundational step in imaging-based spatial biology that determines the accuracy of everything that follows. Identifying where one cell ends and another begins in densely ...

Spatial transcriptomics may have just achieved single-cell resolution. Researchers led by Evan Macosko, Fei Chen, and colleagues at the Broad Institute in Cambridge, Massachusetts, bound together ...

The interdisciplinary field of spatial biology continues to connect omics research with the goal of understanding the spatial distribution of biomolecules that influence biological processes and ...

The surface touch extraction imaging (STEi) method could benefit food scientists, toxicologists, and other laboratory scientists by enabling spatial analysis of samples with irregular surfaces for ...

Spot-based spatial transcriptomics platforms capture gene expression at defined tissue coordinates, but each measurement spot typically encompasses more than one cell. Spatial deconvolution addresses ...