The cell cycle is governed by a network of surveillance mechanisms that detect DNA lesions and coordinate repair with progression through G1, S, G2 and M phases. Central to this system are sensor ...
Many cancer-driving mutations disable a key checkpoint in the cell’s cycle between growth and division, resulting in unchecked activity of the E2F family of transcription factor proteins. A set of ...
This study presents a comprehensive investigation into the prognostic significance of CCCRGs in HCC. Notably, our research provides the first mechanistic evidence that CENPI promotes HCC malignant ...
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