An international research team has uncovered a new mechanism crucial to the production of cellular proteins. When this mechanism is disrupted, the blueprints used by the cell to produce proteins are ...

"Nevertheless, our cells can produce several hundred thousand different proteins," explains Prof. Ivan Đikić from the Institute of Biochemistry II at Goethe University Frankfurt. This diversity is ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Pancreatic cancer ...

Spliceosomal introns are noncoding DNA sequences located between exons in many eukaryotic protein-coding genes. Most are ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

Acute myeloid leukemia (AML) is one of the most aggressive blood cancers and is characterized by the rapid growth of immature myeloid precursor cells. It predominantly affects elderly people, and ...

Splicebio S.L. has gained IND clearance from the FDA for its lead program SB-007, a protein splicing gene therapy to address the root genetic cause of Stargardt disease. The company plans to initiate ...

Influenza A virus dismantles paraspeckles, small RNA-scaffolded structures inside the cell nucleus, to suppress antiviral ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular process ...