The viral life cycle can be divided into two temporally distinct phases: infection and replication. Infection results in the introduction of the viral genome into the cell. This leads to an early ...

There are several types of viral vectors that can be used to deliver nucleic acids into the genetic makeup of cells, including retrovirus, lentivirus, adenovirus, adeno-associated virus and herpes ...

Amplicon infection induces a cascade of innate responses that can result in tissue-dependent restriction of transgene expression. Amplicon-mediated transgene expression is at least partially silenced ...