MSP: Methylation-specific PCR; MSRE: Methylation-sensitive restriction endonucleases; QMSP: Quantitative, methylation-specific PCR; X: Methylation associated with prognosis. Mohammad Obaidul Hoque, ...

MASPIN (“tumor suppressor shield”): MASPIN is a natural defense protein that blocks tumor invasion, regulates cell migration and angiogenesis, promotes apoptosis, and enhances treatment sensitivity.

Contemporary diagnosis of very low risk prostate cancer in a multi-centered hospital system. Use of the Prostatype P-score to predict adverse pathology (AP) at radical prostatectomy (RP). This is an ...

Summary: Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks. This process is mediated by ...

Prospective monitoring of circulating tumor cells in breast cancer patients treated with primary systemic therapy—A translational project of the German Breast Group study GeparQuattro No significant ...

New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been discovered. New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been discovered ...

Researchers have developed a blood test that can reliably detect neuroendocrine prostate cancer and differentiate it from castration-resistant prostate cancer-adenocarcinoma (CRPC-adeno). Like a ...

Figure 5: Analysis of glucose-dependent PDX1 activity and metabolic markers in prostate cancer cells. The study was led by first author Tayo A. Adeyika and corresponding author Bernard Kwabi-Addo from ...

CDKN2A is one of the body’s most important natural defenses against cancer. Often called the “cell cycle brake,” this gene tells cells when to stop dividing and helps damaged cells self-destruct. In ...

Findings show that Telomir-1 restores the body’s natural tumor suppressor defenses by reversing abnormal DNA methylation of MASPIN and RASSF1A – genes that help block invasion, limit metastasis, and ...