Millions of Americans rely on this drug, but a few kitchen habits can quietly undermine it.

Methotrexate is a primary disease-modifying anti-rheumatic drug (DMARD) used to treat rheumatoid arthritis (RA) by reducing inflammation and suppressing the immune system. The American College of ...

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Methotrexate remains a cornerstone in the treatment of rheumatoid arthritis and other rheumatic diseases. Folate antagonism is known to contribute to the antiproliferative effects that are important ...

There have been a lot of questions about medical care and treatment in the wake of the overturning of Roe v. Wade, the landmark legislation that previously made abortion legal in the U.S. on a federal ...

Methotrexate injectable intravenous (IV) solution is only available as a generic drug. It doesn’t have a brand-name version. Methotrexate comes in four forms: injectable IV solution, self-injectable ...

Less frequent laboratory monitoring for established methotrexate users does not appear to compromise patient safety or delay toxicity detection.

Acute renal failure occurs in approximately 2% of patients who receive high-dose methotrexate for the treatment of a hematologic cancer. 1–3 Despite the frequency of acute renal failure and the ...

This story was updated on Oct. 31, 2022, with comments from Joel Gelfand, MD, MSCE. People taking methotrexate for immunomodulatory diseases can skip one or two scheduled doses after they get an ...

St. Jude Children's Research Hospital scientists have identified factors that influence how children with acute lymphoblastic leukemia (ALL) respond to methotrexate. High-dose methotrexate is a part ...

A traditional Chinese herbal remedy used to relieve joint pain and inflammation works as well as methotrexate, a standard drug treatment that is frequently prescribed to control the symptoms of active ...