Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, ...
Spatial transcriptomics has transformed brain research by preserving single-cell molecular resolution within intact tissue coordinates. The brain, organized across cortical layers, long-range ...
Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.
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