Editors have retracted a 2019 study claiming that acteoside suppresses inflammation in osteoarthritic rats after duplicated ...

In this Healio video, James Fernandez, MD, PhD, discusses how signaling pathways such as activated PI3 kinase delta syndrome, JAK-STAT and others are benefiting from an evolving understanding of ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Leveraging advanced spatial proteomics, scientists have identified the JAK/STAT pathway as a critical target for treating toxic epidermal necrolysis, offering new hope for patients with this ...

Epidemiology links AA and atopy: up to 40% of AA patients have atopic comorbidities, and concurrent AD predicts poorer response and relapse. Immune profiling shows mixed Th1/Th2/Th22 activation with ...