As the human brain takes shape before birth, a remarkable type of stem cell helps give it many of the features that make it ...

Human neuroblastoma cell lines, particularly SH-SY5Y, have become central to studies of human neuronal differentiation owing to their reproducibility, ease of culture and capacity to adopt mature ...

A human-specific gene influences brain immune cell development. These cells, called microglia, mature much slower than in ...

Scientists discovered that human microglia, immune cells that help shape developing brain circuits, can take four to eight years to mature instead of just weeks as they do in mice. The unusually slow ...

The human brain contains billions of neurons, specialized nerve cells that receive, transmit and process information through ...

The brain's mechanisms for repairing injuries caused by trauma or degenerative diseases are not yet known in detail. Now, a study by the University of Barcelona describes a new strategy based on stem ...

In a 2022 study, scientists transplanted a cluster of human neurons into developing rat brains and discovered that these cells integrated and matured alongside rat neurons. 1 The researchers could ...

Alzheimer's drugs can slow damage, but they can't replace lost brain cells. A new approach to neuron regeneration could change that.

A new bioengineered neuronal circuit board "BioConNet" allows scientists to artificially engineer human brain-like wiring at scale and can be used to engineer any possible circuit. The fully ...

A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides new insights into human development. The research, published in eLife, is ...

What if amyloid plaques are not the whole story of Alzheimer's disease? New research suggests that a broad range of Alzheimer ...