Patterns of fat metabolism in fibroblasts surrounding the tumor cells direct whether epithelial cancer cells become more ...

The research group of Prof. Sanjiv Luther at the Department of Immunobiology of the University of Lausanne has discovered ...

Fibroblasts are an essential component of the heart, as they play key roles in its structure, development and response to cardiac damage. In this context, a recent study led by the University of ...

Cancer-associated fibroblasts (CAFs) get a bad rap. The protective, gel-like complex surrounding tumors have been thought to be a no-go for drugs and are known to enforce treatment resistance. But ...

A new study in Cell Reports offers fresh evidence that fibroblasts actively shape inflammatory environments in skin disease. Using single-cell RNA sequencing and multiplexed error-robust fluorescence ...

Cancer-associated fibroblasts (CAFs) are crucial in melanoma metastasis, influencing tumor microenvironments and patient outcomes, especially in immunotherapy contexts. Single-cell RNA sequencing ...

L uis Garza, a physician-scientist at Johns Hopkins University School of Medicine for over a decade, noticed a common issue when treating people with limb amputations at his clinic. They often had ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

Regular erections could be important for maintaining erectile function, according to a new study on mice published in Science by researchers at Karolinska Institutet. “We discovered that an increased ...