He began searching for novel parasite-fighting immune cells. McKenzie knew that IL-25 triggers a class of T cells called type-2 helper T cells (Th2s) to proliferate and produce IL-13, and he wondered ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...

All cellular life—from humans to bacteria—possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways—ways that have important implications for the development of ...

A team involving researchers from Wroclaw Medical University analyzed studies of people with schizophrenia spectrum disorders and mood disorders, including depression and bipolar disorder. They found ...

Herd immunity occurs when enough people in a group are immune to a specific infection that it cannot spread easily from person to person. Vaccination programs have been successful in creating herd ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...