A new review in the Journal of Molecular Medicine explains how trained immunity, driven by epigenetic and metabolic ...

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary ...

A first-of-its-kind shot that promises to reverse aging was just injected into a human body. It's a pivotal moment for longevity science, the first opportunity for researchers to prove that epigenetic ...

Age reversal has moved from laboratory theory into a real human experiment. ER-100 could help reveal how much of aging biology is actually reversible.

Direct reprogramming of human blood cell precursors into neural stem cells gradually reversed molecular signs of aging.

Researchers from the University Hospital of Bonn and the University of Bonn have succeeded in dramatically rejuvenating human ...

BOSTON, Aug. 26, 2025 (GLOBE NEWSWIRE) -- Life Biosciences ("Life Bio"), a biotechnology company pioneering cellular rejuvenation therapies to reverse and prevent multiple diseases of aging, today ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Understanding the mechanisms of low temperature-induced epigenetic reprogramming may therefore inform cancer treatments. All in all, this research shows that the genome isn't a fixed instruction ...

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...

An experimental therapy addresses aging cells in the eye that can lead to vision loss.

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...