To adapt to changing environmental pressures, bacteria have developed various methods that allow them to uptake exogenous DNA and incorporate it into their own genomes. One of these processes is ...
A new wave of antibody-targeted anticancer therapies is showing great clinical promise, with the potential to transform cancer treatment. These antibody-drug conjugates (ADCs) are multicomponent ...
Antibodies are widely employed in the quantification of antigens in complex biological samples. Using techniques such as Western blotting, ELISA, and immunohistochemistry researchers are able to ...
Glycosite-specific conjugation has emerged as a gold standard for developing next-generation Antibody-Drug Conjugates (ADCs) and other XDCs. However, most existing approaches are hindered by ...
Dr Ishwar Singh, Senior Lecturer, School of Pharmacy, University of Lincoln, UK discusses about his areas of research, their objectives and the evolving sphere of pharma research, with Lakshmipriya ...
A new study published in Engineering reveals that cinnamic acid, a widely used food additive found in cinnamon, can effectively inhibit plasmid‑mediated conjugation, a major route for the global ...
Unlike current approaches where bioconjugation is typically done following the manufacture of the monoclonal antibody and the cytotoxic drug, the new method begins with the antibody supernatants and ...
Recent collaboration offers more heterogeneous, stable antibody drug conjugates of synthetic tubulin-binding agents shown to rapidly trigger cancer cell death. Targeted drug delivery remains a ...
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