A new preclinical study reports that atovaquone, an approved antiparasitic drug, was reformulated into lactoferrin-based ...
Complement activation is common in patients with systemic lupus erythematosus (SLE), resulting in hypocomplementemia and deposition of complement at sites of tissue damage. The availability of mice ...
It was called ‘complement’ because it aided the antibacterial activity of antibodies. However, it is now known that the complement system can be activated early in an infection without the presence of ...
The complement system is primarily a host defence mechanism, but it causes injury to tissue cells through the formation of the membrane attack complex (C5b–C9), which leads to cell lysis and cell ...
Introduction: IgA nephropathy (IgAN) is the most common primary glomerulonephritis. The first symptoms of IgAN are erytrocyturia or hematuria, proteinuria, and decline in renal function, or any ...
Leptospirosis, a neglected zoonotic disease caused by spirochetes of the genus Leptospira, is responsible for more than one ...
These findings suggest complement protein levels may be an important biomarker for type 1 diabetes. Disruption of the complement system appears to precede the onset of islet autoimmunity (IA), making ...
Laparoscopic D2 gastrectomy with complete mesogastrium excision (D2+CME) to reduce cancer leak from mesogastrium in patients with advanced gastric cancer. This is an ASCO Meeting Abstract from the ...
The results of receiver operator characteristic curve analysis verified that extracellular vesicles expressing MPO+, MPO+C3a+, MPO+C4d+, and MPO+TCC+ were able to distinguish patients with active ...