'Click clotting' stops bleeding fast and could transform emergency care

Researchers at McGill University have developed a rapid way to engineer blood clots that stop severe bleeding and support ...
GEN

Novel Leukemia Target Found in RNA-Binding Cell Surface Protein

In 2021, the lab of chemical biologist and Nobel Laureate Carolyn Bertozzi, PhD, professor at Stanford University, characterized a new type of cell-surface protein, termed glycoRNAs, that form highly ...
GEN

Cell Surface Marker Profiling with Spectral Cytometry Optimizes CAR T Manufacturing

Not all patients respond well to chimeric antigen receptor (CAR) T cell therapies, which reprogram a patient’s own immune cells to recognize and attack cancer. A way to optimize these treatments is to ...
Rutland Herald

Sapient Launches Tumor Protein Mapping Platform to Characterize Functional Biology Across Critical Dimensions in Human Tumors

Sapient, a leader in multi-omics data generation for biomarker discovery and clinical insight delivery, has announced the launch of its Tumor Protein Mapping Platform as a suite of mass ...
mskcc.org

Cell Surface Protein uPAR May Hold the Key to Targeting Solid Tumors with CAR T Cell Therapy

Dr. Scott Lowe, Chair of the Cancer Biology and Genetics Program and Scientific Director of the Marie-Josée and Henry R. Kravis Cancer Ecosystems Project, co-led a team that developed a new type of ...
EurekAlert!

Deciphering the RNA landscapes on mammalian cell surfaces

Cell-surface RNAs, including glycoRNAs, have been described, yet their precise composition across primary cell types remains unresolved, in part due to technical challenges in preserving membrane ...
Labroots

Determination Of Cell Surface Markers On Circulating Immune Cells As Biomarkers For Disease Monitoring Using Spectral Flow Cytometry

The identification of reliable biomarkers from peripheral blood is crucial for improving disease diagnosis and monitoring. Spectral flow cytometry has emerged as a powerful tool for high-dimensional ...