In eukaryotes, the cell cycle consists of four discrete phases: G 1, S, G 2, and M. The S or synthesis phase is when DNA replication occurs, and the M or mitosis phase is when the cell actually ...

New research shows that the transcription factor C/EBPβ normally restrains an inflammatory interferon and TNF-α program that, ...

Checkpoint inhibitors are antibody-based cancer therapies that unlock the immune system’s natural ability to fight cancer. These treatments work by blocking special proteins called immune checkpoints, ...

In a new paper published in Cancer Research, researchers at MUSC Hollings Cancer Center have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can ...

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...

Just like a runaway eighteen-wheeler on the interstate is a scary sight to behold, an immune system without brakes can quickly transform from a cherished protector to a host’s worst nightmare. To ...